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Metastasis Mechanisms

Metastasis is the mechanism by which cancer cells migrate from the original tumor to other organs, and it is a top contributor to mortality from cancer. The lecture "Metastasis Mechanisms" aims to comprehend the biological mechanisms, molecular pathways, and drivers of cancer spread.".

Cancer cells acquire genetic and epigenetic alterations that enable them to invade contiguous tissues, enter the blood or lymphatics, and settle in distant organs. Important processes include epithelial-mesenchymal transition (EMT), angiogenesis, immune escape, and interactions between the tumor and its microenvironment. Knowledge of these processes is crucial to the development of therapies to prevent or restrict metastatic dissemination.

This session also examines new research on molecular targets, metastasis-associated signaling pathways and biomarkers. New therapeutic approaches, such as targeted therapies, immunotherapies, and inhibitors of metastatic pathways, are under investigation to enhance patient survival and decrease recurrence.

Participants will be updated on the intricate biology of metastasis, models used to study the spread of cancer, and new strategies for preventing and treating metastatic cancer. This session highlights the importance of gaining a better understanding of metastasis mechanisms to improve cancer therapy and enhance long-term survival for patients.

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