Tumor biology is the investigation of the cellular, molecular, and genetic processes that generate cancer growth, progression, and metastasis. The session "Tumor Biology" is dedicated to exploring the intricate interactions between tumor cells, the microenvironment, and immune system, which are key to the development of successful cancer treatment.".
The key processes are cell proliferation, apoptosis, angiogenesis, invasion, and metastasis. The molecular changes like oncogene activation, loss of tumor suppressors, epigenetic changes, and deregulation of the signaling pathways are key to tumor growth and heterogeneity. Knowledge of the above processes aids in the identification of therapeutic targets and predictive markers.
The session also addresses the tumor microenvironment, such as immune cells, stromal elements, and interactions with extracellular matrix, which impact tumor behavior, treatment efficacy, and resistance. Progress in genomics, proteomics, and single-cell analyses reveals greater insights into tumor biology and allows precision medicine approaches to be developed in individual patients.
Participants will learn about basic mechanisms, clinical relevance, and research breakthroughs in tumor biology. This session highlights how knowing the complex biology of tumors can inform targeted therapies, enhance treatment success, and drive innovation in personalized oncology.