The human microbiome—the assemblage of microbes that inhabit and cover the body—has a pivotal impact on cancer formation, growth, and treatment response. The session "Cancer Microbiome" is dedicated to interactions between microbial communities and tumors, with an emphasis on their relevance to oncology research and clinical practice.".
Research indicates that microbiome composition and diversity can impact immune system function, inflammation, and metabolism, all of which have implications in cancer initiation and development. Some microbial patterns have been associated with elevated cancer risk, whereas others might improve therapy responsiveness, including immunotherapy. Elucidation of these connections offers promise for new diagnostic, prognostic, and treatment approaches.
The session also covers interventions against the microbiome, including probiotics, prebiotics, dietary changes, and transplantation of microbiota, to enhance treatment response. Technologies such as metagenomics and sophisticated bioinformatics can provide in-depth profiles of microbial communities and functional roles in the tumor environment.
Participants will learn about the two-way interplay between cancer and the microbiome, new research discoveries, and future clinical possibilities. This session highlights how tapping into the microbiome could unlock new prevention opportunities, precision therapy, and better patient outcomes in oncology.